![]() Preoperative pupil dilation is commonly achieved by repeated administration of mydriatic drops. 2 An adequately dilated pupil is a prerequisite for safe cataract extraction surgery, and small pupil size has been shown to be associated with increased risk for intraoperative and early postoperative complications. This study is the first report of improved mydriatic efficacy in diabetic patients.Ĭataract is the leading cause of age-related blindness worldwide, 1 and cataract extraction is the most commonly performed ophthalmic surgery. Gel formulation achieved significantly greater pupil dilation than drops, despite a lower concentration of phenylephrine, and was also associated with significantly lower patient discomfort. ![]() Use of the gel achieved an even greater degree of pupil dilation in this subset of patients than drops ( P=0.019). In diabetic patients, pupil size was smaller at baseline and following instillation of drops and gel. Use of the gel achieved greater mydriasis than drops ( P=0.01), and was also associated with lower pain scores ( P=0.003). There was no difference in pupil size at baseline. Pain upon instillation was measured by visual analog scale (VAS). ![]() Pupil size was measured by a Colvard pupillometer at baseline and 5, 15, 30, and 45 min following instillation. One eye was dilated with two drops (tropicamide 0.5% and phenylephrine 10%), and the other with one drop of gel (tropicamide 0.5%+phenylephrine 5%). The study included 60 patients with no previous ocular history of trauma and surgery. To compare the efficacy in pupil dilation and degree of discomfort between topical instillation of mydriatic drops and gel.
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